Retinal chromophore of rhodopsin photoisomerizes within picoseconds.

作者: G Hayward , W Carlsen , A Siegman , L Stryer

DOI: 10.1126/SCIENCE.7466366

关键词: RetinalPicosecondRhodopsinRetinaldehydeRaman spectroscopyPhotodissociationPhotochemistryResonanceMaterials scienceIsomerization

摘要: A new picosecond resonance Raman technique shows that lines characteristic of a distorted all-trans retinal appear within 30 picoseconds after photolysis rhodopsin or isorhodopsin. This finding suggests isomerization is nearly complete the absorption photon.

参考文章(18)
Maïté Coppey, Hervé Tourbez, Pierre Valat, Bernard Alpert, Study of haem structure of photo-deligated haemoglobin by picosecond resonance Raman spectra Nature. ,vol. 284, pp. 568- 570 ,(1980) , 10.1038/284568A0
Rich Mathies, Teresa B. Freedman, Lubert Stryer, Resonance Raman studies of the conformation of retinal in rhodopsin and isorhodopsin. Journal of Molecular Biology. ,vol. 109, pp. 367- 372 ,(1977) , 10.1016/S0022-2836(77)80040-5
G. E. Busch, M. L. Applebury, A. A. Lamola, P. M. Rentzepis, Formation and Decay of Prelumirhodopsin at Room Temperatures Proceedings of the National Academy of Sciences of the United States of America. ,vol. 69, pp. 2802- 2806 ,(1972) , 10.1073/PNAS.69.10.2802
TÔRU YOSHIZAWA, GEORGE WALD, Pre-lumirhodopsin and the bleaching of visual pigments. Nature. ,vol. 197, pp. 1279- 1286 ,(1963) , 10.1038/1971279A0
B. Aton, A.G. Doukas, D. Narva, R.H. Callender, U. Dinur, B. Honig, Resonance Raman studies of the primary photochemical event in visual pigments Biophysical Journal. ,vol. 29, pp. 79- 94 ,(1980) , 10.1016/S0006-3495(80)85119-8
B. Honig, T. Ebrey, R. H. Callender, U. Dinur, M. Ottolenghi, Photoisomerization, energy storage, and charge separation: a model for light energy transduction in visual pigments and bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 76, pp. 2503- 2507 ,(1979) , 10.1073/PNAS.76.6.2503
A. R. Oseroff, R. H. Callender, Resonance Raman spectroscopy of rhodopsin in retinal disk membranes. Biochemistry. ,vol. 13, pp. 4243- 4248 ,(1974) , 10.1021/BI00717A027
G. Wald, Molecular Basis of Visual Excitation Science. ,vol. 162, pp. 230- 239 ,(1968) , 10.1126/SCIENCE.162.3850.230
J. Terner, T. G. Spiro, M. Nagumo, M. F. Nicol, M. A. El-Sayed, Resonance Raman spectroscopy in the picosecond time scale: the carboxyhemoglobin photointermediate Journal of the American Chemical Society. ,vol. 102, pp. 3238- 3239 ,(1980) , 10.1021/JA00529A056
G. Eyring, R. Mathies, Resonance Raman studies of bathorhodopsin: evidence for a protonated Schiff base linkage. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 76, pp. 33- 37 ,(1979) , 10.1073/PNAS.76.1.33