Novel insights into the pathogenicity of epidemic Aeromonas hydrophila ST251 clones from comparative genomics.
作者： Maoda Pang , Jingwei Jiang , Xing Xie , Yafeng Wu , Yuhao Dong
DOI: 10.1038/SREP09833
关键词: Outbreak 、 Genomics 、 Genome 、 Microbiology 、 Comparative genomics 、 Virulence 、 Aeromonas hydrophila 、 Phylogenetics 、 Prophage 、 Biology
摘要: Outbreaks in fish of motile Aeromonad septicemia (MAS) caused by Aeromonas hydrophila have caused a great concern worldwide. Here, for the first time, we provide two complete genomes of epidemic A. hydrophila strains isolated in China. To gain an insight into the pathogenicity of epidemic A. hydrophila, we performed comparative genomic analyses of five epidemic strains belonging to sequence type (ST) 251, together with the environmental strain ATCC 7966T. We found that the known virulence factors, including a type III secretion …
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