Endothelin and Experimental Hypertension
作者： Wolfgang Böcker , Detlev Ganten , Martin Paul
DOI: 10.1007/978-3-642-79338-7_1
关键词: Pharmacology 、 Prostacyclin 、 Thromboxane A2 、 Paracrine signalling 、 Vasodilation 、 Endothelin receptor 、 Autocrine signalling 、 Chemistry 、 Renal blood flow 、 Nitric oxide
摘要: The vascular endothelium releases a number of potent vasodilators including nitric oxide and prostacyclin as well the vasoconstrictors thromboxane A2 super anion. Endothelium-derived factors play an important role in autocrine/paracrine regulation tone. This chapter will focus on endothelin family peptides first described by Yanagisawa 1988 following his successful isolation vasoconstrictor peptide from (Yanagisawa et al. 1988).
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