Immunohistochemical demonstration of gastrin in mammalian islets of Langerhans.

摘要: THE relationship between the gastric secretagogue extracted from Zollinger–Ellison tumours1 and antral hormone gastrin2,3 was clarified by Gregory et al.4 who found amino-acid constitution of contained in tumours to be identical that human gastrin. Previous attempts extract normal hog pancreas1 animal pancreas5 were, however, unsuccessful. We have now demonstrated presence gastrin some cells mammalian islets Langerhans indirect immunofluorescent technique. In addition, fluorescent pancreatic were correspond D discovered Bloom6, which recently identified7–10 with argyrophil A1 Hellerstrom Hellman11.