Interaction of hemoglobin E and several forms of alpha-thalassemia in Cambodian families

作者: Kanokwan Sanchaisuriya , Sitthichai Panyasai , Goonnapa Fucharoen , Supan Fucharoen , Lyda Luy

DOI: 10.3324/%X

关键词: HemoglobinopathyHemoglobin Constant SpringAlpha-thalassemiaBiologyHemoglobin EGenotypeMultiplexMultiplex polymerase chain reactionGeneticsThalassemia

摘要: … Hb variant in the proband. As shown in Figure 3, we unexpectedly observed a compound heterozygosity … (I-2) was a pure Hb CS carrier though HbCS was not observed. As summarized …

参考文章(32)
K Sanchaisuriya, N Sae-ung, G Fucharoen, S Fucharoen, A Jetsrisuparb, N Sae-ue, R Baisungneon, Molecular and hematological characterization of HbE heterozygote with alpha-thalassemia determinant. Southeast Asian Journal of Tropical Medicine and Public Health. ,vol. 28, pp. 100- 103 ,(1997)
S.L. Schrier, A. Bunyaratvej, A. Khuhapinant, S. Fucharoen, M. Aljurf, L.M. Snyder, C.R. Keifer, L. Ma, N. Mohandas, The Unusual Pathobiology of Hemoglobin Constant Spring Red Blood Cells Blood. ,vol. 89, pp. 1762- 1769 ,(1997) , 10.1182/BLOOD.V89.5.1762
L Makonkawkeyoon, T Sanguansermsri, T Asato, Y Nakashima, H Takei, Rapid detection of chain termination mutations in the alpha 2 globin gene. Blood. ,vol. 82, pp. 3503- 3504 ,(1993) , 10.1182/BLOOD.V82.11.3503.BLOODJOURNAL82113503
Ahnond Bunyaratvej, Suthat Fucharoen, Albert Greenbaum, Narla Mohandas, Hydration of red cells in α and β thalassemias differs : a useful approach to distinguish between these red cell phenotypes American Journal of Clinical Pathology. ,vol. 102, pp. 217- 222 ,(1994) , 10.1093/AJCP/102.2.217
S Anaokar, P J Garry, J C Standefer, Solid-phase enzyme immunoassay for serum ferritin. Clinical Chemistry. ,vol. 25, pp. 1426- 1431 ,(1979) , 10.1093/CLINCHEM/25.8.1426
Deborah Hurst, Barbara Tittle, Klara M. Kleman, Stephen H. Embury, Bertram H. Lubin, Anemia and hemoglobinopathies in Southeast Asian refugee children. The Journal of Pediatrics. ,vol. 102, pp. 692- 697 ,(1983) , 10.1016/S0022-3476(83)80235-2
Sittichai Panyasai, Patcharawadee Sringam, Goonnapa Fucharoen, Kanokwan Sanchaisuriya, Supan Fucharoen, A Simplified Screening for α-Thalassemia 1 (SEA Type) Using a Combination of a Modified Osmotic Fragility Test and a Direct PCR on Whole Blood Cell Lysates Acta Haematologica. ,vol. 108, pp. 74- 78 ,(2002) , 10.1159/000064746