Delta infection among patients with chronic hepatitis B in the Stockholm region.
作者： G. Lindh , O. Weiland , B. G. Hansson , A. Svedmy
DOI: 10.1007/BF01641021
关键词: Epidemiology 、 Medicine 、 Chronic Active 、 Gastroenterology 、 Liver biopsy 、 Cirrhosis 、 Hepatitis 、 Antibody 、 Radioimmunoassay 、 Internal medicine 、 Immunology 、 Antigen
摘要: The prevalence, epidemiology and consequences of delta infection were analysed in 60 patients attending the Roslagstull Hospital for Infectious Diseases, Stockholm, Sweden, between 1972 1982. All had biopsy-documented chronic hepatitis B. Using radioimmunoassay techniques, sera from all tested antibodies to A virus, B surface antigen corresponding antibody, core antigen, hepatatitis e antibody antigen. underwent a liver biopsy which was repeated 28 patients. 32% (19/60) found be anti-delta positive. majority positive either immigrants non-European countries or addicts (both 9/19 47%). Infections with agent have already occurred Stockholm region early 1970s. During study period, four developed clinical laboratory signs acute association infection. Among patients, 63% (12/19) classified as having active hepatitis, without cirrhosis, against 39% (16/41) negative Histological progression cirrhosis observed two initial persistent hepatitis.
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sci-hub.se 参考文章(21)
M. Rizzetto, J. W. k. Shih, J. L. Gerin, The hepatitis B virus-associated delta antigen: isolation from liver, development of solid-phase radioimmunoassays for delta antigen and anti-delta and partial characterization of delta antigen. Journal of Immunology. ,vol. 125, pp. 318- 324 ,(1980)
O. Weiland, P. Lundbergh, J. V. R. Berg, B. Bjorvatn, B. Flehmig, Acute viral hepatitis A, B and non-A, non-B in Stockholm in the 1950s and 1970s: a comparison. Infection. ,vol. 9, pp. 268- 274 ,(1981) , 10.1007/BF01640989
Antonina Smedile, Pietro Dentico, Alessandro Zanetti, Evangelista Sagnelli, Erik Nordenfelt, Giovanni C. Actis, Mario Rizzetto, Infection with the Delta (δ) Agent in Chronic HBsAg Carriers Gastroenterology. ,vol. 81, pp. 992- 997 ,(1981) , 10.1016/S0016-5085(81)80003-0
M. Rizzetto, B. Hoyer, M. G. Canese, J. W. Shih, R. H. Purcell, J. L. Gerin, delta Agent: association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees Proceedings of the National Academy of Sciences of the United States of America. ,vol. 77, pp. 6124- 6128 ,(1980) , 10.1073/PNAS.77.10.6124
T Moestrup, B G Hansson, A Widell, E Nordenfelt, Clinical aspects of delta infection. BMJ. ,vol. 286, pp. 87- 90 ,(1983) , 10.1136/BMJ.286.6359.87
Mario Rizzetto, Giorgio Verme, Ferruccio Bonino, Serafino Recchia, Hans Popper, Antonio Picciotto, Massimo Colombo, Patrizia Farci, Renata Calzia, Sarino Aricò, Chronic Hepatitis in Carriers of Hepatitis B Surface Antigen, with Intrahepatic Expression of the Delta Antigen Annals of Internal Medicine. ,(2020)
Mario Rizzetto, GIORGIO VERME, SERAFINO RECCHIA, FERRUCCIO BONINO, PATRIZIA FARCI, SARINO ARICÒ, RENATA CALZIA, ANTONIO PICCIOTTO, MASSIMO COLOMBO, HANS POPPER, Chronic Hepatitis in Carriers of Hepatitis B Surface Antigen, with Intrahepatic Expression of the Delta Antigen: An Active and Progressive Disease Unresponsive to Immunosuppressive Treatment Annals of Internal Medicine. ,vol. 98, pp. 437- 441 ,(1983) , 10.7326/0003-4819-98-4-437
Mario Rizzetto, RobertH. Purcell, JohnL. Gerin, EPIDEMIOLOGY OF HBV-ASSOCIATED DELTA AGENT: GEOGRAPHICAL DISTRIBUTION OF ANTI-DELTA AND PREVALENCE IN POLYTRANSFUSED HBsAg CARRIERS The Lancet. ,vol. 315, pp. 1215- 1219 ,(1980) , 10.1016/S0140-6736(80)91678-5
Mario Rizzetto, DavidJ. Gocke, Giorgio Verme, JamesW.-K. Shih, RobertH. Purcell, JohnL. Gerin, INCIDENCE AND SIGNIFICANCE OF ANTIBODIES TO DELTA ANTIGEN IN HEPATITIS B VIRUS INFECTION The Lancet. ,vol. 314, pp. 986- 990 ,(1979) , 10.1016/S0140-6736(79)92561-3
B. Flehmig, M. Ranke, H. Berthold, H.-J. Gerth, A Solid-Phase Radioimmunoassay for Detection of IgM Antibodies to Hepatitis A Virus The Journal of Infectious Diseases. ,vol. 140, pp. 169- 175 ,(1979) , 10.1093/INFDIS/140.2.169