The study of DNA fingerprint of hydatidiform moles and the clinical outcome

摘要: OBJECTIVE To study the genetic origin of hydatidiform moles (HM) and clinical outcome. METHODS 41 cases mole were collected mainly from Beijing area studied for components by DNA fingerprints. The diagnosis persistent gestational trophoblastic disease (PTD) was made if blood hCG remained higher than normal 8 weeks after evacuation. RESULTS Among HM samples, 32 produced identifiable only paternal found in 21, which 6 PTD, both parents 11, none developed PTD. CONCLUSIONS more frequently HM, there a risk PTD former group latter.