作者: Jose Muñoz , Raquel Montes , Mireia Baeza
DOI: 10.1016/J.TRAC.2017.08.012
关键词: Transducer 、 Analyte 、 Nanocomposite 、 Capacitive sensing 、 Electrode 、 Dielectric spectroscopy 、 Materials science 、 Surface engineering 、 Highly sensitive 、 Nanotechnology
摘要: Abstract Electrochemical Impedance Spectroscopy (EIS) has gained widespread application for the characterization of functionalized electrode surfaces and transduction bio-sensing events. However, bio-sensors using EIS detection have to be carefully designed minimize non-specific binding analyte. In this sense, surface engineering by nanocomposite materials (NCs) is advantageous due increased area, improved electrical conductivity sensing interface, chemical accessibility analyte electroanalysis. Accordingly, review summarizes basis technique as well its implementation not only in common Faradaic (impedimetric) NCs highly sensitive transducer platforms but also so conventional non-Faradaic (capacitive) approaches. Finally, it highlighted feasibility an alternative tool towards optimization NC electrodes terms loading ratios electroanalytical improvements, summarizing latest promising results carbon paste electrodes.