Side Effects Of Drugs Essay: Third-generation oral contraceptives: time to look again?

摘要: Publisher Summary This chapter presents discusses the adverse effects of third-generation oral contraceptives and their successor. In mid- 1990s, a team at Leiden University in The Netherlands advanced evidence that well-defined subpopulation individuals particular risk third generation exist; it comprised carriers thrombogenic factor V mutation. When 126 women fertile age who had episodes deep vein thrombosis were compared with 259 control subjects, highest age-adjusted relative for was found to be associated product based on desogestrel; lower risks all other types contraceptive. work delineated nature thromboembolic as whole, defined more clearly susceptible groups, also underlined problem attached products generation. Of progestogens have emerged still recently from laboratory (the so-called fourth generation), drospirenone has been most prominent, having developed contraceptive purposes series combinations an estrogen.