Stably transfected rodent fibroblast cell lines expressing human GABA-A -receptors

作者: Karen Hadingham , Paul John Whiting

DOI:

关键词: ReceptorTransfectionFibroblastAlpha (ethology)Gamma subunitRecombinant DNAGABAA receptorMolecular biologyCell cultureBiologyCell biology

摘要: The present invention relates to stably co-transfected eukaryotic cell lines capable of expressing a recombinant GABAA receptor, particularly human which comprises at least one alpha, beta and gamma subunit; the use line and/or membrane preparation in selecting compounds designing medicaments interact with respective receptor.

参考文章(3)
Le Bourdelles Beatrice, Wingrove Peter Baxter, Handingham Karen Louise, Whiting Paul John, Gaba-A receptor subunits (alpha-2, alpha-3, alpha-5, alpha -6, beta-2) and transfected cells expressing them ,(2002)
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