ACETYL LYSINE INCORPORATION WITH tRNA SYNTHETASE
作者： Heinz Neumann , Jason Chin
DOI:
关键词: Mutation (genetic algorithm) 、 Lysine 、 Peptide sequence 、 Biochemistry 、 Chemistry 、 Transfer RNA 、 Sequence identity 、 Genetics
摘要: The invention relates to a tRNA synthetase capable of binding Ne-acetyl lysine, wherein said comprises polypeptide having at least 90 % sequence identity the amino acid MbPyIRS, and L266M mutation.
lens.org 参考文章(61)
Andrew J. Bannister, Philip Zegerman, Janet F. Partridge, Eric A. Miska, Jean O. Thomas, Robin C. Allshire, Tony Kouzarides, Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. ,vol. 410, pp. 120- 124 ,(2001) , 10.1038/35065138
Michael Grunstein, Histone acetylation in chromatin structure and transcription Nature. ,vol. 389, pp. 349- 352 ,(1997) , 10.1038/38664
Monika Lachner, Dónal O'Carroll, Stephen Rea, Karl Mechtler, Thomas Jenuwein, Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. ,vol. 410, pp. 116- 120 ,(2001) , 10.1038/35065132
Christophe Dhalluin, Justin E. Carlson, Lei Zeng, Cheng He, Aneel K. Aggarwal, Ming-Ming Zhou, Ming-Ming Zhou, Structure and ligand of a histone acetyltransferase bromodomain Nature. ,vol. 399, pp. 491- 496 ,(1999) , 10.1038/20974
Karolin Luger, Thomas J. Rechsteiner, Timothy J. Richmond, Preparation of nucleosome core particle from recombinant histones. Methods in Enzymology. ,vol. 304, pp. 3- 19 ,(1999) , 10.1016/S0076-6879(99)04003-3
Oliver Rackham, Jason W Chin, A network of orthogonal ribosome·mRNA pairs Nature Chemical Biology. ,vol. 1, pp. 159- 166 ,(2005) , 10.1038/NCHEMBIO719
Qing Li, Hui Zhou, Hugo Wurtele, Brian Davies, Bruce Horazdovsky, Alain Verreault, Zhiguo Zhang, Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly. Cell. ,vol. 134, pp. 244- 255 ,(2008) , 10.1016/J.CELL.2008.06.018
Van A.T. Huynh, Philip J.J. Robinson, Daniela Rhodes, A Method for the In Vitro Reconstitution of a Defined “30 nm” Chromatin Fibre Containing Stoichiometric Amounts of the Linker Histone Journal of Molecular Biology. ,vol. 345, pp. 957- 968 ,(2005) , 10.1016/J.JMB.2004.10.075
Michael Bruno, Andrew Flaus, Chris Stockdale, Chantal Rencurel, Helder Ferreira, Tom Owen-Hughes, Histone H2A/H2B Dimer Exchange by ATP-Dependent Chromatin Remodeling Activities Molecular Cell. ,vol. 12, pp. 1599- 1606 ,(2003) , 10.1016/S1097-2765(03)00499-4
Anil Ozdemir, Salvatore Spicuglia, Edwin Lasonder, Michiel Vermeulen, Coen Campsteijn, Hendrik G. Stunnenberg, Colin Logie, Characterization of Lysine 56 of Histone H3 as an Acetylation Site in Saccharomyces cerevisiae Journal of Biological Chemistry. ,vol. 280, pp. 25949- 25952 ,(2005) , 10.1074/JBC.C500181200