Wada memory performance predicts seizure outcome after epilepsy surgery in children

作者: Gregory P. Lee , Yong D. Park , Michael Westerveld , Ann Hempel , Lynn B. Blackburn

DOI: 10.1046/J.1528-1157.2003.05003.X

关键词: Anterior temporal lobectomyAnesthesiaEpilepsyPediatricsLateralization of brain functionRecognition memoryPsychologyEpilepsy surgeryWada testMemoriaAmobarbital

摘要: Summary: Purpose: Wada memory asymmetries were examined in children from four comprehensive epilepsy surgery centers who subsequently underwent to determine whether performance could predict degree of seizure relief children. Methods: One hundred fifty-six (between ages 5 and 16 years) with intractable testing before resective (93 within the left hemisphere, 63 right hemisphere). Memory stimuli presented soon after intracarotid amobarbital injection, recognition for items was assessed return neurologic baseline. Eighty-eight unilateral temporal lobe resection, 68 had extratemporal resections. (67%) free (Engel class I), 52 (33%) not classes II–IV) at follow-up (mean interval, 2.3 years). Results: Seizure-free recalled 19.3% more ipsilateral injection than did non–seizure-free (p = 0.008). If analysis restricted youngsters lobectomies (TLs), seizure-free 27.7% TL 0.004). With regard individual patient prediction, 75% score consistent focus free. In contrast, only 56% whose inconsistent 0.01). Conclusions: Results suggest that are related adolescents.

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