Concentrating mixtures of neuroactive pharmaceuticals and altered neurotransmitter levels in the brain of fish exposed to a wastewater effluent.
作者： Arthur David , Anke Lange , Charles R. Tyler , Elizabeth M. Hill
DOI: 10.1016/J.SCITOTENV.2017.11.265
关键词: Amitriptyline 、 Neurotransmitter 、 Fluoxetine 、 Benzodiazepine 、 Tricyclic 、 Chemistry 、 Serotonin 、 Reuptake inhibitor 、 Pharmacology 、 Sertraline
摘要: … higher in brain compared with blood plasma, showing these … In contrast with these reports however, there have been some … We identified 14 different neuroactive compounds in extracts …
sussex.ac.uk
sci-hub.se 参考文章(40)
Zhengxin Xie, Guanghua Lu, Sheng Li, Yang Nie, Binni Ma, Jianchao Liu, Behavioral and biochemical responses in freshwater fish Carassius auratus exposed to sertraline Chemosphere. ,vol. 135, pp. 146- 155 ,(2015) , 10.1016/J.CHEMOSPHERE.2015.04.031
Ralf Regenthal, Mario Krueger, Claus Koeppel, Rainer Preiss, Drug levels: therapeutic and toxic serum/plasma concentrations of common drugs. Journal of Clinical Monitoring and Computing. ,vol. 15, pp. 529- 544 ,(1999) , 10.1023/A:1009935116877
Parvathy Prasad, Satoshi Ogawa, Ishwar S. Parhar, Role of serotonin in fish reproduction Frontiers in Neuroscience. ,vol. 9, pp. 195- 195 ,(2015) , 10.3389/FNINS.2015.00195
Gordon Paterson, Chris D. Metcalfe, Uptake and depuration of the anti-depressant fluoxetine by the Japanese medaka (Oryzias latipes). Chemosphere. ,vol. 74, pp. 125- 130 ,(2008) , 10.1016/J.CHEMOSPHERE.2008.08.022
H. Friedman, DarrellR. Abernethy, DavidJ. Greenblatt, RichardI. Shader, The pharmacokinetics of diazepam and desmethyldiazepam in rat brain and plasma. Psychopharmacology. ,vol. 88, pp. 267- 270 ,(1986) , 10.1007/BF00180822
J.P. Sumpter, R.L. Donnachie, A.C. Johnson, The apparently very variable potency of the anti-depressant fluoxetine Aquatic Toxicology. ,vol. 151, pp. 57- 60 ,(2014) , 10.1016/J.AQUATOX.2013.12.010
Roberto Romero González, Remedios Fernández Fernández, José Luis Martínez Vidal, Antonia Garrido Frenich, María Luz Gómez Pérez, Development and validation of an ultra-high performance liquid chromatography-tandem mass-spectrometry (UHPLC-MS/MS) method for the simultaneous determination of neurotransmitters in rat brain samples. Journal of Neuroscience Methods. ,vol. 198, pp. 187- 194 ,(2011) , 10.1016/J.JNEUMETH.2011.03.023
Theodore W. Valenti, Georgianna G. Gould, Jason P. Berninger, Kristin A. Connors, N. Bradley Keele, Krista N. Prosser, Bryan W. Brooks, Human Therapeutic Plasma Levels of the Selective Serotonin Reuptake Inhibitor (SSRI) Sertraline Decrease Serotonin Reuptake Transporter Binding and Shelter-Seeking Behavior in Adult Male Fathead Minnows Environmental Science & Technology. ,vol. 46, pp. 2427- 2435 ,(2012) , 10.1021/ES204164B
Mitchell S. Kostich, Angela L. Batt, James M. Lazorchak, Concentrations of prioritized pharmaceuticals in effluents from 50 large wastewater treatment plants in the US and implications for risk estimation Environmental Pollution. ,vol. 184, pp. 354- 359 ,(2014) , 10.1016/J.ENVPOL.2013.09.013
Svante Winberg, Arthur A Myrberg, Jr, Göran E Nilsson, Agonistic Interactions Affect Brain Serotonergic Activity in an Acanthopterygiian Fish: The Bicolor Damselfish (Pomacentrus partitus) Brain Behavior and Evolution. ,vol. 48, pp. 213- 220 ,(1996) , 10.1159/000113199