Effect of a single intrauterine administration of recombinant bovine interferon-τ on day 7 of the estrous cycle on the luteal phase length and blood profile in dairy cows

作者: S. Matsunaga , T. Osawa , M. Geshi , H. Takahashi , S. Inumaru

DOI: 10.1016/J.RVSC.2011.05.006

关键词: Estrous cycleEndocrinologyInternal medicineCorpus luteumUterusPlaceboLuteal phaseRespiratory rateBovine serum albuminOvulationBiology

摘要: This study tested the effect of recombinant bovine interferon-tau (rboIFN-τ) on length estrous cycle, luteal lifespan and side effects rboIFN-τ in cow. A normal cycle six non-lactating cycling Holstein cows was observed (non-treated cycle), either 2.0 mg liposomalized (treated cycle) or serum albumin (BSA; placebo infused uterus day 7 (day 0=day ovulation). Rectal temperature, heart rate respiratory were recorded blood samples collected before after treatments. The corpus luteum treated cycles not significantly different from those non-treated cycles. In contrast, treatment caused a transient increase rectal temperature decrease number peripheral lymphocytes neutrophils treatment.

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