Socioeconomic inequalities and oral cancer risk: A systematic review and meta‐analysis of case‐control studies

作者: David I. Conway , Mark Petticrew , Helen Marlborough , Julien Berthiller , Mia Hashibe

DOI: 10.1002/IJC.23430

关键词: Socioeconomic statusMedicineDemographyCancerSocial classConfoundingRisk factorMeta-analysisCase-control studySurgeryOdds ratio

摘要: There is uncertainty and limited recognition of the relationship between socioeconomic inequalities oral cancer. We aimed to quantitatively assess association status (SES) cancer incidence risk. A systematic review case-control studies obtained published unpublished estimates SES risk related Studies were included which reported odds ratios (ORs) corresponding 95% CIs with respect SES, or if could be calculated obtained. Meta-analyses performed on subgroups: measure, age, sex, global region, development level, time-period lifestyle factor adjustments; while sensitivity analyses conducted based study methodological issues. Forty-one provided 15,344 cases 33,852 controls met our inclusion criteria. Compared individuals who in high strata, pooled ORs for developing 1.85 (95%CI 1.60, 2.15; n = 37 studies) those low educational attainment; 1.84 (1.47, 2.31; 14) occupational social class; 2.41 (1.59, 3.65; 5) income. Subgroup showed that was significantly associated increased lower income-countries, across world, remained when adjusting potential behavioural confounders. Inequalities persist but are perhaps reducing over recent decades. Oral significant comparable factors. Our results provide evidence steer health policy focus lifestyles factors toward an integrated approach incorporating measures designed tackle root causes disadvantage.

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