作者: Asma Wasfi , Falah Awwad , Ahmad I. Ayesh
DOI: 10.1016/J.BIOSX.2019.100011
关键词: Nanopore 、 DNA 、 Density functional theory 、 Zigzag 、 DNA sequencing 、 Nanotechnology 、 Graphene 、 Nucleobase 、 Materials science 、 Conductance
摘要: Abstract DNA sequencing witnessed significant research efforts to improve its efficiency and reduce the production cost. Successful of quick low cost techniques associate with personalized medicine as well procedures different genetics subfields applications. In this article, a novel two-terminal z-shaped sensor is developed studied detect sequence nucleobases. The consists two metallic zigzag graphene nanoribbon (ZGNR), semiconducting channel made armchair (AGNR), nanopore in middle through which nucleobases are translocated. First-principle modeling non-equilibrium Green's function along density functional theory (NEGF + DFT), utilized investigate device. Various electronic characteristics investigated, including transmission spectrum, conductance, electrical current inside sensors' nanopore. particular, these properties variation nucleobase orientation. resulted unique signatures for individual four placed within