Nutrient availability, the microbiome, and intestinal transport during pregnancy

作者: Stuart Astbury , Alison Mostyn , Michael E. Symonds , Rhonda C. Bell

DOI: 10.1139/APNM-2015-0117

关键词: Gastrointestinal tractIntestinal absorptionPrenatal Nutritional Physiological PhenomenaFetusLactationBiologyEndocrinologyGastrointestinal MicrobiomeMicrobiomePhysiologyPregnancyInternal medicine

摘要: Adequate adaptation of the gastrointestinal tract is important during pregnancy to ensure that increased metabolic demands by developing fetus are met. These include changes in surface area mediated villus hypertrophy and enhanced functional capacity individual nutrient receptors, including those transporting glucose, fructose, leucine, calcium. processes regulated either demand or facilitated secretion hormones. Our review also covers recent research into microbiome, how could lead microbial adaptations, which beneficial mother, yet similar seen syndrome. The potential role diet modulating microbiome pregnancy, as well for intestinal microbiota induce complications, examined. Gaps current literature highlighted, where only historical evidence available, we suggest areas should be a priority further research. In summary, although significant degree has been described, there both well-established more discoveries, such within maternal pose new questions effectively adapts especially conjunction with obesity.

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