Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain.
作者： Haiyan Fu , Joseph Muenzer , Richard J Samulski , George Breese , Jerillyn Sifford
DOI: 10.1016/J.YMTHE.2003.08.021
关键词: Transgene 、 Viral vector 、 Gene delivery 、 Central nervous system 、 Vector (molecular biology) 、 Adeno-associated virus 、 Reporter gene 、 Gene expression 、 Molecular biology 、 Biology
摘要: The blood–brain barrier is the main obstacle to efficient delivery of therapeutic reagents, including viral vectors, into the central nervous system (CNS) for treating global CNS diseases. …
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