Estimation of the safe use concentrations of the preservative 1,2-benzisothiazolin-3-one (BIT) in consumer cleaning products and sunscreens

作者: Rachel M. Novick , Mindy L. Nelson , Kenneth M. Unice , James J. Keenan , Dennis J. Paustenbach

DOI: 10.1016/J.FCT.2013.02.006

关键词: Allergic contact dermatitisBit (key)Food sciencePreservative1 2 benzisothiazolin 3 oneDermal exposureSkin sensitizationLaundry detergentSensitizationChemistry

摘要: 1,2-Benzisothiazolin-3-one (BIT; CAS # 2634-33-5) is a preservative used in consumer products. Dermal exposure to BIT at sufficient dose and duration can produce skin sensitization …

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