作者: Steven Greenberg , Sergio Grinstein
DOI: 10.1016/S0952-7915(01)00309-0
关键词: Microbiology 、 Biology 、 Entry into host 、 Immunity 、 Actin 、 Innate immunology 、 Pathogen 、 Innate immune system 、 Phagocytosis 、 Cell biology 、 Apoptosis 、 Immunology 、 Immunology and Allergy
摘要: Phagocytosis is an evolutionarily conserved process utilized by many cells to ingest microbial pathogens, and apoptotic necrotic corpses. Recent investigation has revealed a fundamental requirement for two co-ordinated cellular processes--cytoskeletal alterations membrane trafficking--in the phagocytic event. Some elements of this machinery are co-opted certain pathogens gain entry into host cells.