TSH-receptor antibodies in mothers with Graves' disease and outcome in their offspring.
作者： Nobuo Matsuura , Kenji Fujieda , Yasuhiro Iida , Seiichiro Fujimoto , Junji Konishi
DOI: 10.1016/S0140-6736(88)91001-X
关键词: Medicine 、 Endocrinology 、 Thyroid function 、 Antibody 、 Thyroid 、 Pregnancy 、 Gestation 、 Receptor 、 Graves' disease 、 Internal medicine 、 Offspring
摘要: Blood was taken from 56 selected newborn babies whose mothers had Graves' disease, to assess the relation between their thyroid function and presence of thyrotropin (TSH) binding inhibitor immunoglobulins (TBII) stimulating antibodies (TSAb) in maternal serum. All thyrotoxic both these TSH receptor However, most been well controlled pregnancy gave birth normal babies. 15 a transient syndrome low serum thyroxine (T4) free T4 with this tended be associated (TBII 9/15, TSAb 4/15). 2 infants hyperthyroxinaemia without hyperthyroidism showed strong activity TBII activity.
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