In vitro osteogenic induction of human gingival fibroblasts for bone regeneration.
作者： Nesrine Z Mostafa , Hasan Uludağ , Mathew Varkey , Douglas N Dederich , Michael R Doschak
DOI: 10.2174/1874210601105010139
关键词: Periodontitis 、 Dental alveolus 、 Cancer research 、 Dexamethasone 、 Tooth loss 、 In vitro 、 Tissue engineering 、 Medicine 、 Dentistry 、 Bone regeneration
摘要: Background And Objective: Periodontitis is an inflammatory disease causing bone loss, and a primary cause of tooth loss. Gingival fibroblasts are readily available with minimal donor site morbidity may be ideal for tissue engineering efforts in regenerating lost alveolar bone. Dexamethasone (Dex) commonly employed vitro osteogenic induction variety cells, but its effect on human gingival (HGF) still controversial. Therefore, the aim our study was to investigate differentiation HGF following Dex treatment.
benthamopen.com
sci-hub.st 参考文章(27)
H. R. Haase, S. Ivanovski, M. J. Waters, P. M. Bartold, Growth hormone regulates osteogenic marker mRNA expression in human periodontal fibroblasts and alveolar bone-derived cells Journal of Periodontal Research. ,vol. 38, pp. 366- 374 ,(2003) , 10.1034/J.1600-0765.2003.00655.X
Jeremy Saklatvala, Glucocorticoids: do we know how they work? Arthritis Research. ,vol. 4, pp. 146- 150 ,(2002) , 10.1186/AR398
IG Needleman, E Giedrys-Leeper, RJ Tucker, HV Worthington, Guided tissue regeneration for periodontal infra-bony defects The Cochrane Database of Systematic Reviews. ,(2006) , 10.1002/14651858.CD001724
Takanori Iwata, Masayuki Yamato, Zheng Zhang, Shigeki Mukobata, Kaoru Washio, Tomohiro Ando, Jan Feijen, Teruo Okano, Isao Ishikawa, Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use. Journal of Clinical Periodontology. ,vol. 37, pp. 1088- 1099 ,(2010) , 10.1111/J.1600-051X.2010.01597.X
MINNA M. SANDBERG, HANNU T. ARO, EERO I. VUORIO, Gene expression during bone repair. Clinical Orthopaedics and Related Research. pp. 292- 312 ,(1993) , 10.1097/00003086-199304000-00043
Mathew Varkey, Cezary Kucharski, Michael R. Doschak, Shelley R. Winn, Elsa J. Brochmann, Samuel Murray, John R. Matyas, Ronald F. Zernicke, Hasan Uludag, Osteogenic Response of Bone Marrow Stromal Cells from Normal and Ovariectomized Rats Treated with a Low Dose of Basic Fibroblast Growth Factor Tissue Engineering. ,vol. 13, pp. 809- 817 ,(2007) , 10.1089/TEN.2006.0348
S. Ivanovski, H. Li, H. R. Haase, P. M. Bartold, Expression of bone associated macromolecules by gingival and periodontal ligament fibroblasts. Journal of Periodontal Research. ,vol. 36, pp. 131- 141 ,(2001) , 10.1034/J.1600-0765.2001.360301.X
Bruno Braga Benatti, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enílson Antônio Sallum, Francisco Humberto Nociti Jr, None, Physiological features of periodontal regeneration and approaches for periodontal tissue engineering utilizing periodontal ligament cells. Journal of Bioscience and Bioengineering. ,vol. 103, pp. 1- 6 ,(2007) , 10.1263/JBB.103.1
Elerin Kärner, Christian Unger, Alastair J. Sloan, Lars Ährlund-Richter, Rachael V. Sugars, Mikael Wendel, Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro. Stem Cells and Development. ,vol. 16, pp. 39- 52 ,(2007) , 10.1089/SCD.2006.0010
M. Shimonishi, J. Hatakeyama, Y. Sasano, N. Takahashi, T. Uchida, M. Kikuchi, M. Komatsu, In vitro differentiation of epithelial cells cultured from human periodontal ligament. Journal of Periodontal Research. ,vol. 42, pp. 456- 465 ,(2007) , 10.1111/J.1600-0765.2007.00969.X