Anthelmintic resistance of injectable macrocyclic lactones in cattle: A systematic review and meta-analysis

作者: Barbara Haline Buss Baiak , Cheila Roberta Lehnen , Raquel Abdallah da Rocha

DOI: 10.1590/S1984-296120180093

关键词: Odds ratioMeta-analysisConfidence intervalAnthelminticOddsForest plotInternal medicineBiology

摘要: The purpose of this work was to identify, critically assess, and summarize available data from primary research about the anthelmintic resistance injectable macrocyclic lactones in cattle. Meta-analysis performed estimate pooled Odds Ratio 95% Confidence Intervals. Of 1504 abstracts screened for eligibility, 80 were deemed relevant full publication review. Thirteen publications included qualitative synthesis assessed systematic bias. Only five studies quantitative analysis because they showed a low risk producing biased results all parameters. forest plot indicated four that discuss (P<0.05), while only one study did not (P<0.05). 0.59 (95% intervals: 0.08, 0.47) times higher odds report than reporting efficacious treatment, with significant substantially heterogeneity (I2=25%). Anthelmintic is reality. There are need improve methodological studies, which problem investigations involves review meta-analysis (SR-MA).

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