Preterm neonatal cardiovascular instability: does understanding the fetus help evaluate the newborn?

摘要: Preterm newborns, particularly very low birth weight frequently experience intermittent hypotension and/or hypoperfusion. Organ perfusion is largely distinct from systemic hypotension, suggesting that changes in underlying vascular tone are the major determinants of perfusion. fetuses have a remarkable anaerobic tolerance and ability to survive insults with no or limited injury, balanced by relative immaturity key autonomic responses. Exposure hypoxia-ischaemia infection trigger complex evolve over many days there evidence these centrally controlled linked, part, organ metabolism. Hypoperfusion occurs after without injury occurring. Hypoxia-ischaemia, clinical interventions, such as steroid therapy ventilation, can interact increase decrease risk brain injury.