Aryl and heteroaryl compounds, compositions, and methods of use
作者： Robert Rothlein , Devi Reddy Gohimmukkula , Adnan M.M. Mjalli , Christopher Behme , Daniel Peter Christen
DOI:
关键词: Coagulation 、 Factor XIa 、 Aryl 、 Chemistry 、 Factor IX 、 Organic chemistry 、 Antagonist
摘要: This invention provides aryl and heteroaryl compounds, methods of their preparation, pharmaceutical compositions comprising the use in treating human or animal disorders. The compounds may be antagonists, partial antagonist factor IX and/or XI thus, useful for inhibiting intrinsic pathway blood coagulation. a variety applications including management, treatment control diseases caused part by clotting pathway..
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