Multicenter Cross-sectional Study of Patients with Rheumatoid Arthritis in Greece: Results from a cohort of 2.491 patients

摘要: Aim of the study To evaluate current disease characteristics, treatment and comorbidities rheumatoid arthritis (RA) in Greece. Methods Multicenter, cross-sectional with a 9-month recruitment period between 2015 2016. Demographics, were collected via web-based platform. Results 2.491 RA patients recruited: 96% from tertiary referral centers, 79% females mean age 63.1 years duration 9.9 years. Fifty-two percent factor and/or anti-CCP positive, while 41% had erosive disease. Regarding treatment, 82% on conventional synthetic modifying anti-rheumatic drugs (csDMARDs), 42% biologic DMARDs (TNFi: 22%, non-TNFi: 20%) 40% corticosteroids (mean daily dose: 5.2 mg). Despite therapy, 36% moderate 12% high activity. The most frequent hypertension (42%), hyperlipidemia (33%), osteoporosis (29%), diabetes mellitus (15%) depression (12%). Latent tuberculosis infection (positive tuberculin skin test or interferon gamma release assay) was diagnosed 13 15.3% patients, respectively. chronic viral infections, 6.2% history herpes zoster 2% 0.7% hepatitis B C virus infection, A serious documented 9.6%. Only 52% participants ever been vaccinated against pneumococcus influenza virus, Conclusion This is one largest epidemiologic studies providing valuable data regarding characteristics Half seropositive but despite half displayed residual activity, preventive vaccination limited.