New chiral derivatizing agents: convenient determination of absolute configurations of free amino acids by 1H NMR.
作者： Michio Kurosu , Kai Li
DOI: 10.1021/OL8028719
关键词: Nuclear magnetic resonance spectroscopy 、 Proton NMR 、 Absolute (perfumery) 、 Computational chemistry 、 Chemistry 、 Nitrogen 、 Free amino 、 Chiral derivatizing agent 、 Reagent 、 Organic chemistry 、 Stereoisomerism
摘要: The chiral carbonate reagents 5 allow for the direct and unambiguous determination of absolute configurations a wide range free amino acids using (1)H NMR. By approximately 3:1 mixture (S)-5 (R)-5, corresponding carbamates are determined by only analyzing nitrogen protons.
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