Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore.
作者： Andrea Urbani , Valentina Giorgio , Andrea Carrer , Cinzia Franchin , Giorgio Arrigoni
DOI: 10.1038/S41467-019-12331-1
关键词: Voltage-dependent anion channel 、 ATP synthase 、 Adenosine triphosphate 、 Biophysics 、 Heart metabolism 、 Ligand (biochemistry) 、 Adenine nucleotide 、 Chemistry 、 Mitochondrial permeability transition pore 、 ATP hydrolysis
摘要: … a colorimetric assay that detects inorganic phosphate liberated from ATP 63 . Nonenzymatic degradation of ATP under these conditions was <10% of the total phosphate. One unit of …
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