Geriatric oncology

摘要: Due to the ageing of population and sharp increase in life expectancy, cancer older person has become an increasingly common problem Western world. Although several authors have stressed that elderly patients deserve special attention as a target group for research efforts, aged are still less likely be offered participation clinical trials. The cellular molecular mechanisms regulating physiological process senescence far from understood, although inflammation is play important role, at least some cancers. In addition, relationship between risk also understood. One most intriguing aspects how different person; basis this variation largely unknown. Population-based studies longitudinal surveys shown comorbidity physical mental functioning factors; thus, meaningful assessment disability should implemented practice. Modern geriatrics targeted towards with multiple problems. Such not simply old, but geriatric because interacting psychosocial As consequence, health status old persons cannot evaluated by merely describing single disease, and/or measuring response, or survival after treatment. Conversely, it necessary conduct more comprehensive investigation 'functional status' person. A consultation provides variety relevant information enables healthcare team manage complexity care elderly; referred Comprehensive Geriatric Assessment (CGA). use CGA now being introduced into oncological definition frailty controversial represents major issue debate geriatrics. frail increases, trials needed. usefulness these requires consensus frailty. Clearly, management acquisition skills evaluation recognition emergencies well experience case management.