Methods and compositions concerning the vegfr-2 gene (kinase domain receptor, kdr)
作者： Federico Innocenti , Xin Ye , Elisa Cerri , Wanqing Liu
DOI:
关键词: Genotype 、 Disease 、 Receptor 、 Cancer research 、 Protein kinase domain 、 VEGF receptors 、 Kinase insert domain receptor 、 Phenotype 、 Gene 、 Biology
摘要: The present invention concerns methods and compositions related to evaluating variants in the vascular endothelial growth factor receptor 2 (VEGFR-2) using this information yield phenotypic these genotypes. In certain embodiments, are provided which a variant indicates an altered level of expression VEGFR-2 gene (KDR). Additionally, prognosis patient with angiogenesis-dependent disease or condition for optimizing dosage anti-angiogenic therapy guiding treatment selection provided.
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