Effects of Various Stimulators and Inhibitors on the Respiratory Burst of PMNL with Aging

作者: Zsuzsa Varga , Gabriella Foris , Sàndor Szucs , Tamàs Fülöp , Andràs Leovey

DOI: 10.1007/978-1-4613-0513-2_20

关键词: NADPH oxidaseRespiratory burstChronic granulomatous diseaseDiabetes mellitusImmune systemImmunologyMedicineIncidence (epidemiology)NADPH oxidase activityPertussis toxin

摘要: It is well known that the incidence of certain diseases such as infections (Gardner, 1980), atherosclerosis (Stout, 1987), diabetes mellitus (DeFronzo, 1981), and tumors (Doll et al., 1970) increased with aging. can be assumed cause this multifactorial, but decrease immune response certainly plays an important role (Makinodan Kay, 1980; Corberand 1981). was established oxidative burst essential in host defense against pathogens other microorganisms (Johnston 1976; Babior Crowley, 1983); therefore, alteration respiratory could contribute to infectious

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