Protein phosphatases: Structure, regulation, and function

摘要: Publisher Summary The reversible phosphorylation of proteins is an essential component almost all signaling pathways in a living cell. Changes the state protein are conducted by two types enzyme activities: kinases that catalyze covalent attachment phosphate group to amino acid side chain and phosphatases reverse this process. Nearly aspects cell function involve phosphorylation. Some examples include metabolism, cell-cycle progression, ion transport, developmental control, stress responses. This diverse spectrum cellular functions reflected large number intracellular subject Several approaches have already been taken study plant phosphatases—for example, genetic screening identified abscisic acid–insensitive (ABI) pathway related (ABA) signaling. biochemical properties highly conserved among eukaryotic organisms. Efforts need be directed functional analysis these enzymes context biology.