Atherosclerosis and Inflammatory Heart Disease

作者: DeLisa Fairweather

DOI: 10.1007/978-1-61779-812-2_11

关键词: Dilated cardiomyopathyRheumatoid arthritisHeart failureImmunologyMyocarditisHeart diseaseStrokeDiseaseInflammationMedicine

摘要: Cardiovascular disease (CVD) is the leading cause of mortality ­worldwide, with atherosclerosis accounting for most deaths. Inflammation a key component in pathogenesis CVDs such as atherosclerosis, stroke, myocarditis, dilated cardiomyopathy, and heart failure. A number recent clinical animal model findings suggest that autoimmune may be linked. Many potentially modifiable risk factors like diet, tobacco smoking, infections have been associated increased cardiovascular both several diseases including systemic lupus erythematosus, rheumatoid arthritis. Although many are more prevalent women, developing CVD remains elevated men. Future studies should examine sex differences biomarkers following infection and/or toxicant exposure.

参考文章(115)
S. M. Rappaport, M. T. Smith, Environment and Disease Risks Science. ,vol. 330, pp. 460- 461 ,(2010) , 10.1126/SCIENCE.1192603
Reza Ashrafi, Pankaj Garg, Ewan McKay, John Gosney, Som Chuah, Gershan Davis, Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review Cardiology Research and Practice. ,vol. 2011, pp. 578390- 578390 ,(2011) , 10.4061/2011/578390
J. Agüero, J. Navarro, M.C. Medina, L. Almenar, M. Chirivella, L. Martínez-Dolz, J.A. Moro, I. Sánchez-Lazaro, V. Ortiz, R. Raso, A. Salvador, Clinical variables associated with the presence of inflammatory infiltrates in patients with dilated cardiomyopathy undergoing heart transplantation. Congress of the Andalusian Society of Organ and Tissue Transplantation (SATOT). ,vol. 40, pp. 3017- 3019 ,(2008) , 10.1016/J.TRANSPROCEED.2008.09.010
Joshua A. Beckman, Mark A. Creager, Peter Libby, Diabetes and Atherosclerosis: Epidemiology, Pathophysiology, and Management JAMA. ,vol. 287, pp. 2570- 2581 ,(2002) , 10.1001/JAMA.287.19.2570
Maarten Hulsmans, Paul Holvoet, The vicious circle between oxidative stress and inflammation in atherosclerosis. Journal of Cellular and Molecular Medicine. ,vol. 14, pp. 70- 78 ,(2010) , 10.1111/J.1582-4934.2009.00978.X
Zbigniew Gaciong, Bartosz Symonides, Hypertension 2010: what was new for the cardiologist? Expert Opinion on Pharmacotherapy. ,vol. 11, pp. 2579- 2597 ,(2010) , 10.1517/14656566.2010.513972
ABDEL-MOHSEN NOMEIR, Cardiac involvement in rheumatoid arthritis. Annals of Internal Medicine. ,vol. 79, pp. 800- 806 ,(1973) , 10.7326/0003-4819-79-6-800
Shanta R. Dube, DeLisa Fairweather, William S. Pearson, Vincent J. Felitti, Robert F. Anda, Janet B. Croft, Cumulative childhood stress and autoimmune diseases in adults. Psychosomatic Medicine. ,vol. 71, pp. 243- 250 ,(2009) , 10.1097/PSY.0B013E3181907888
Christina K. Yung, Victoria L. Halperin, Gordon F. Tomaselli, Raimond L. Winslow, Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes. Genomics. ,vol. 83, pp. 281- 297 ,(2004) , 10.1016/J.YGENO.2003.08.007