Cellularity of rat adipose tissue: effects of growth, starvation, and obesity

摘要: The size, number, and rate of formation mature adipocytes were studied in the epididymal pads retroperitoneal adipose depots Sprague-Dawley rat. Early growth these was accompanied by progressive enlargement cells as well increases number. Beyond 15th wk life, depot grew exclusively process cellular enlargement, with no further change cell Severe starvation during 6th life followed normal feeding had lasting effect on size or number; prolonged semistarvation beginning greatly reduced while number unaffected. Likewise, extreme produced hypothalamic lesions did not but only size. concept a fixed adult organism may be central importance caloric metabolic equilibrium.