Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure

作者: Daniela Predoi , Simona Iconaru , Mihai Predoi , Nicolas Buton , Mikael Motelica-Heino

DOI: 10.3390/COATINGS9030156

关键词: NanoparticleSpin coatingSol-gelDynamic light scatteringMaterials scienceScanning electron microscopeNuclear chemistryZincThin filmBiocompatibility

摘要: In this study, ZnHAp layers deposited on a Si substrate were obtained by sol-gel spin-coating procedure. The solutions used to obtain the coatings investigated dynamic light scattering (DLS) analysis, ζ-potential, ultrasound measurements, and flame atomic absorption spectrometry (AAS). average measured hydrodynamic diameter from DLS measurements analyzed so as characterize estimate stability of nanoparticles. AAS results confirmed presence zinc in gels preparation layers. X-ray diffraction (XRD) scanning electron microscopy (SEM). XRD revealed peaks hexagonal hydroxyapatite all samples. morphology annealed at 500 • C (ZnHAp-500) 700 (ZnHAp-700), which evidenced that no fissures or cracks formed surface coatings. biocompatibility assays indicated did not present any toxicity towards HeLa cells. Furthermore, study regarding cytotoxicity against microorganisms emphasized exhibited an inhibitory effect S. aureus bacterial cells also C. albicans fungal

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