作者: John P. Hayslett , George L. Cohn
DOI: 10.1056/NEJM196704272761708
关键词: Pathology 、 Spontaneous remission 、 Disease 、 Gastroenterology 、 Hyperplasia 、 Adrenal abnormalities 、 Average duration 、 Cushing's disease 、 Internal medicine 、 Benign adenoma 、 Medicine 、 Adrenal carcinoma 、 General Medicine
摘要: SINCE Cushing1 called attention to the syndrome that now bears his name, it has been recognized clinical manifestations of Cushing's disease are associated with adrenocortical hyper-function and secretion excessive amounts cortisol. The adrenal abnormalities may be classified as nontumorous hyperplasia, benign adenoma carcinoma. Although intensity symptoms vary, disorder characterized by an unfavorable prognosis a progressively deteriorating course. life expectancy2 untreated patient is reported three ten years, average duration five seven years. Patients malignant tumors . . .