Treatment and diagnosis of cardiac hypertrophy
作者： Richard A. Shimkets , David G. Lowe
DOI:
关键词: Pathology 、 Gene 、 Function (biology) 、 Nucleotide 、 Bioinformatics 、 Amino acid 、 Differentially expressed genes 、 Biology 、 Cardiac hypertrophy
摘要: The present invention is based upon the identification of genes which are differentially expressed in hypertrophic cardiac tissue as compared to normal tissue. Accordingly, provides nucleotide sequences selected from group consisting CH-1, CH-2, CH-3, CH-4, CH-5, CH-6, CH-7, CH-8, and CH-9, amino acid their encoded proteins, well derivatives (e.g., fragments) analogs thereof. also therapeutic methods pharmaceutical compositions on promotion or inhibition function genes. further diagnosis, prognosis screening for a disposition diseases disorders associated with hypertrophy. Methods modulators protein products hypertrophy additionally provided.
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