Intra- and Interprotein Phosphorylation between Two-hybrid Histidine Kinases Controls Myxococcus xanthus Developmental Progression
作者： Andreas Schramm , Bongsoo Lee , Penelope I. Higgs
关键词: Phosphorylation 、 Biochemistry 、 Biology 、 Regulation of gene expression 、 Histidine 、 Myxococcus xanthus 、 Protein turnover 、 Kinase 、 Signal transduction
摘要: Background: His-Asp phosphorelay proteins can be components of complex signaling systems. Results: Two hybrid histidine kinases, EspA and EspC, form a complex; phosphorylates both receiver modules to regulate proteolytic turnover regulatory protein. Conclusion: kinases are integrated by inter- intra-histidine aspartate phosphotransfer. Significance: A novel signal transduction mechanism was identified.
mpg.de
sci-hub.se 参考文章(69)
Bongsoo Lee, Andreas Schramm, Sakthimala Jagadeesan, Penelope I. Higgs, TWO-COMPONENT SYSTEMS AND REGULATION OF DEVELOPMENTAL PROGRESSION IN MYXOCOCCUS XANTHUS Methods in Enzymology. ,vol. 471, pp. 253- 278 ,(2010) , 10.1016/S0076-6879(10)71014-4
Kamalendu Nath, Arthur L. Koch, Protein degradation in Escherichia coli. I. Measurement of rapidly and slowly decaying components. Journal of Biological Chemistry. ,vol. 245, pp. 2889- 2900 ,(1970) , 10.1016/S0021-9258(18)63072-8
I M Arias, D Doyle, R T Schimke, Studies on the synthesis and degradation of proteins of the endoplasmic reticulum of rat liver. Journal of Biological Chemistry. ,vol. 244, pp. 3303- 3315 ,(1969) , 10.1016/S0021-9258(18)93128-5
David E. Whitworth, Myxobacteria : multicellularity and differentiation Myxobacteria. Multicellularity and differentiation.. ,(2007)
K A O'Connor, D R Zusman, Behavior of peripheral rods and their role in the life cycle of Myxococcus xanthus. Journal of Bacteriology. ,vol. 173, pp. 3342- 3355 ,(1991) , 10.1128/JB.173.11.3342-3355.1991
W Hsing, T J Silhavy, Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli. Journal of Bacteriology. ,vol. 179, pp. 3729- 3735 ,(1997) , 10.1128/JB.179.11.3729-3735.1997
Sumiko Inouye, Hirofumi Nariya, José Muñoz-Dorado, 11 Protein Ser/Thr Kinases and Phosphatases in Myxococcus xanthus American Society of Microbiology. pp. 191- 210 ,(2008) , 10.1128/9781555815677.CH11
Frank-Dietrich Müller, Anke Treuner-Lange, Johann Heider, Stuart M Huntley, Penelope I Higgs, Global transcriptome analysis of spore formation in Myxococcus xanthus reveals a locus necessary for cell differentiation. BMC Genomics. ,vol. 11, pp. 264- 264 ,(2010) , 10.1186/1471-2164-11-264
Penelope I. Higgs, Sakthimala Jagadeesan, Petra Mann, David R. Zusman, EspA, an Orphan Hybrid Histidine Protein Kinase, Regulates the Timing of Expression of Key Developmental Proteins of Myxococcus xanthus Journal of Bacteriology. ,vol. 190, pp. 4416- 4426 ,(2008) , 10.1128/JB.00265-08
Robert B Bourret, Receiver domain structure and function in response regulator proteins. Current Opinion in Microbiology. ,vol. 13, pp. 142- 149 ,(2010) , 10.1016/J.MIB.2010.01.015