作者: Alfonso Ciccone , Luca Valvassori , Michele Nichelatti , Annalisa Sgoifo , Michela Ponzio
关键词: Stroke 、 Randomized controlled trial 、 Anesthesia 、 Medicine 、 Case fatality rate 、 Fibrinolytic agent 、 Atrial fibrillation 、 Odds ratio 、 Adverse effect 、 Standard treatment
摘要: A total of 181 patients were assigned to receive endovascular therapy, and intravenous t-PA. The median time from stroke onset the start treatment was 3.75 hours for therapy 2.75 t-PA (P<0.001). At 3 months, 55 in endovascular-therapy group (30.4%) 63 (34.8%) alive without disability (odds ratio adjusted age, sex, severity, atrial fibrillation status at baseline, 0.71; 95% confidence interval, 0.44 1.14; P = 0.16). Fatal or nonfatal symptomatic intracranial hemorrhage within 7 days occurred 6% each group, there no significant differences between groups rates other serious adverse events case fatality rate. Conclusions results this trial with acute ischemic indicate that is not superior standard (Funded by Italian Medicines Agency, ClinicalTrials.gov number, NCT00640367.)