Progesterone solutions for increased bioavailability

摘要: Fill materials for hydrophobic drugs, such as progesterone, and methods of making using thereof are described herein. The fill material contains the drug dissolved in one or more fatty acids. concentration is typically from about 7% to 50% by weight material. acids 60% 95% carrier. formulation also an organic acid both pharmaceutically acceptable alcohols mono-, di-, triesters medium long chain can be encapsulated a hard soft capsule. formulations herein have higher dissolution rate faster onset compared micronized progesterone suspended oil thus should increased bioavailability vivo.