FGF21 mutant fusion polypeptides and uses thereof

作者: Agnes Eva Hamburger , Edward John Belouski , Randy Ira Hecht , Murielle Marie Ellison , Jeonghoon Sun

DOI:

关键词: FusionBiochemistryNucleic acidBiologyMutant

摘要: The invention provides nucleic acid molecules encoding FGF21 mutant fusion polypeptides comprising mutations at positions 98, 171, 179, 180 or 181, polypeptides, pharmaceutical compositions and methods for treating metabolic disorders using such acids, compositions.

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