Enzyme immunoassays for parasitic diseases.

作者: A. Voller , Ann Bartlett , D.E. Bidwell

DOI: 10.1016/0035-9203(76)90163-2

关键词: MedicineEnzyme immunoassaysDisease controlMass screeningComplement fixation testMalariaSerologyIntensive care medicineDegree of precisionTrypanosomiasis

摘要: It is only in recent years that serology has come to play a major role parasitic diseases. At first complement fixation was most used but gradually more convenient and sensitive techniques such as gel precipitation (DRAPER, 1976), agglutination methods (KAGAN, 1974) were introduced. Probably the serological test by parasitologists been immunofluorescence, particularly indirect fluorescent antibody method 1974; AMBROISE-THOMAS, 1976). Certain factors must be taken into consideration when assessing usefulness of for The parasitoses malaria, schistosomiasis, trypanosomiasis, infect millions people poor areas world where technical expertise is, at present, very limited. In these can use establishing epidemiological indices monitoring disease control programmes. Tests should suitable mass screening, simple cheap, .the results available quickly. Under conditions some degree precision may have sacrificed interests practicability. There also place sophisticated individual diagnosis infections especially privileged world. We feel enzyme-immunoassays, enzyme-linked immunosorbent assay, part both above situations.

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