Clinical significance of basal-like subtype in triple-negative breast cancer

作者: Yutaka Yamamoto , Mutsuko Ibusuki , Masahiro Nakano , Teru Kawasoe , Ryousuke Hiki

DOI: 10.1007/S12282-009-0150-8

关键词: CancerProgesterone receptorBreast cancerEstrogen receptorMedicineTriple-negative breast cancerOncologyClinical significanceSurgical oncologyBasal (phylogenetics)Internal medicine

摘要: Background No clinically useful target molecule has been identified for triple-negative (TN) breast cancer, i.e., estrogen receptor (ER)-negative, progesterone (PgR)-negative, human epidermal growth factor receptor-2 (HER2)-negative phenotype, and its prognosis is poor. Triple-negative cancer consists of two subtypes: basal-like non-basal-like. The aim this study to clarify the clinical biological characteristics these subtypes TN cancer.

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