Prevention of Infections During Neurosurgery

作者: Bina Rubinovitch , Ethan Rubinstein

DOI: 10.2165/00023210-199810060-00003

关键词: Intensive care medicineAntibioticsSecond-generation cephalosporinsMedicineNeurosurgeryDrugFuture studiesRegimenPharmacotherapyAntibacterial agentPharmacology (medical)Psychiatry and Mental healthClinical neurology

摘要: Infections associated with neurosurgery can be disastrous. Ample evidence supports the routine use of prophylactic antibacterials in clean, nonimplant neurosurgical procedures to reduce risk wound infections. A recently performed meta-analysis suggests that even units do not antibacterial prophylaxis and have a low infection rate, may still beneficial. Since comparative studies are lacking, selection one regimen over another is somewhat arbitrary. In where prevailing pathogens antibacterial-sensitive Gram-positive cocci, selected should aimed at these pathogens. Antistaphylococcal antibacterials, which most frequently studied agents various first or second generation cephalosporins, suitable for this purpose. Future compare proposed new regimens those already demonstrated effective.

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