Alteraciones en la transmisión sináptica en ratones transgénicos modelo de migraña (S218L) y su modulación por drogas antiepilépticas

作者: Di Guilmi , Mariano Nicolás

DOI:

关键词: Molecular biologyExcitatory synaptic transmissionBiology

摘要: Ratones transgenicos (knock-in, KI) con mutaciones del canal de calcio P/Q fueron utilizados como modelos murinos Migrana Hemiplejica Familiar tipo I. Se estudiaron mediante tecnicas patch-clamp (whole cell) las corrientes presinapticas (IpCa) en los terminales nerviosos gigantes caliz Held y postsinapticas [...]

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