Poor anaerobic threshold and VO2 max recorded during cardiopulmonary exercise testing (CPET) prior to cytoreductive surgery in advanced (stage 3/4) ovarian cancer (AOC) is associated with suboptimal cytoreduction but does not preclude maximum effort cytoreduction.

摘要: This study assessed Cardiopulmonary Exercise Testing (CPET) in predicting oncological outcomes, post-operative recovery and complications advanced ovarian cancer (AOC) cytoreductive surgery. We reviewed all patients who had CPET prior to AOC surgery with evidence of upper abdominal disease on preoperative imaging at the University Hospitals Derby Burton (UHDB) between August 2016 July 2019. Patients were stratified by AT maximum VO2 levels. 43 identified. showed no relationship major complications. 100% AT ≥11 group received R0 (n = 21, 91.30%), or R1 (n = 2, 8.70%) cytoreduction, whereas AT <11 group, only 75.00% achieved resection (p = .02). Surgical complexity was higher ≥11 (p = .001) ≥15 (p = .0006). No other correlations seen max readmissions. difference overall survival if achieved.IMPACT STATEMENTWhat is already known this subject? testing allows pre-operative assessment functional capacity generate variables that can be used as a risk-stratification tool for Whilst has been shown predict morbidity non-gynaecological surgery, it remains unproven despite being increasingly utilised.What do results add? Our data suggest does not complication rates AOC. poor performance are more likely receive suboptimal outcomes from surgery.What implications these findings clinical practice and/or further research? should discount research address interplay nutrition, haematological markers, neoadjuvant chemotherapy performance.