Synthesis of ferrocenyl pyrazoles by the reaction of 3-ferrocenylpropynal with hydrazinium salts
作者： Metin Zora , Ayşe Nur Pinar , Mustafa Odabaşoğlu , Orhan Büyükgüngör , Günseli Turgut
DOI: 10.1016/J.JORGANCHEM.2007.10.035
关键词: Organic chemistry 、 Hydrazine 、 Derivative (chemistry) 、 Pyrazole 、 Medicinal chemistry 、 Ferrocene 、 Chemistry 、 Propynal 、 Ethanol 、 Physical and Theoretical Chemistry 、 Inorganic chemistry 、 Materials Chemistry 、 Biochemistry
摘要: Abstract Synthesis of ferrocenyl-substituted pyrazoles via the reaction between 3-ferrocenylpropynal and hydrazinium salts is described. Depending upon substitution pattern hydrazine derivative, affords 1-alkyl/aryl-5-ferrocenylpyrazoles and/or 1-alkyl/aryl-3-ferrocenylpyrazoles. Structures 5-ferrocenyl-1-phenyl-1H-pyrazole, 1-benzyl-5-ferrocenyl-1H-pyrazole 2-(3-ferrocenylpyrazol-1-yl)ethanol were identified by X-ray crystallography.
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