An Allosteric Self-Splicing Ribozyme Triggered by a Bacterial Second Messenger
作者： E. R. Lee , J. L. Baker , Z. Weinberg , N. Sudarsan , R. R. Breaker
关键词: Ligase ribozyme 、 Ribozyme 、 Group II intron 、 Genetics 、 Riboswitch 、 Biology 、 VS ribozyme 、 Mammalian CPEB3 ribozyme 、 RNA 、 RNA splicing
摘要: … We identified an allosteric group I ribozyme, wherein self-… system resides in the 5′ untranslated region of the messenger … Our findings indicate that some self-splicing ribozymes are …
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Elizabeth E. Regulski, Ronald R. Breaker, In-line probing analysis of riboswitches. Methods of Molecular Biology. ,vol. 419, pp. 53- 67 ,(2008) , 10.1007/978-1-59745-033-1_4
Kristin M Thompson, Heather A Syrett, Scott M Knudsen, Andrew D Ellington, Group I aptazymes as genetic regulatory switches BMC Biotechnology. ,vol. 2, pp. 21- 21 ,(2002) , 10.1186/1472-6750-2-21
Kelly Kruger, Paula J. Grabowski, Arthur J. Zaug, Julie Sands, Daniel E. Gottschling, Thomas R. Cech, Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena Cell. ,vol. 31, pp. 147- 157 ,(1982) , 10.1016/0092-8674(82)90414-7
D.A. Shub, M.-Q. Xu, J.M. Gott, A. Zeeh, L.D. Wilson, A family of autocatalytic group I introns in bacteriophage T4. Cold Spring Harbor Symposia on Quantitative Biology. ,vol. 52, pp. 193- 200 ,(1987) , 10.1101/SQB.1987.052.01.024
Linus Sandegren, Britt-Marie Sjöberg, Self-Splicing of the Bacteriophage T4 Group I Introns Requires Efficient Translation of the Pre-mRNA In Vivo and Correlates with the Growth State of the Infected Bacterium Journal of Bacteriology. ,vol. 189, pp. 980- 990 ,(2007) , 10.1128/JB.01287-06
HUEI-HUN TSENG, ZASHA WEINBERG, JEREMY GORE, RONALD R. BREAKER, WALTER L. RUZZO, Finding non-coding RNAs through genome-scale clustering. Journal of Bioinformatics and Computational Biology. ,vol. 7, pp. 373- 388 ,(2009) , 10.1142/S0219720009004126
Nadia Kulshina, Nathan J Baird, Adrian R Ferré-D'Amaré, Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch. Nature Structural & Molecular Biology. ,vol. 16, pp. 1212- 1217 ,(2009) , 10.1038/NSMB.1701
N. Sudarsan, M. C. Hammond, K. F. Block, R. Welz, J. E. Barrick, A. Roth, R. R. Breaker, Tandem riboswitch architectures exhibit complex gene control functions. Science. ,vol. 314, pp. 300- 304 ,(2006) , 10.1126/SCIENCE.1130716
Henrik Nielsen, Steinar D. Johansen, Group I introns: Moving in new directions RNA Biology. ,vol. 6, pp. 375- 383 ,(2009) , 10.4161/RNA.6.4.9334
Michael D Dambach, Wade C Winkler, Expanding roles for metabolite-sensing regulatory RNAs Current Opinion in Microbiology. ,vol. 12, pp. 161- 169 ,(2009) , 10.1016/J.MIB.2009.01.012