The Initiation Factors
作者： John W. B. Hershey
DOI: 10.1007/978-1-4684-4124-6_3
关键词: Cell biology 、 Eukaryotic Small Ribosomal Subunit 、 Translation (biology) 、 Protein biosynthesis 、 Initiation factor 、 Eukaryotic Ribosome 、 Transcription preinitiation complex 、 Messenger RNA 、 Ribosome 、 Chemistry
摘要: Initiation of protein synthesis is the process whereby ribosome binds mRNA and first aminoacyl-tRNA to form an initiation complex which capable entering elongation phase synthesis. The pathway involves numerous steps: First, 80S dissociates into 40S 60S ribosomal subunits; subunit forms a preinitiation with methionyl-tRNA mRNA; this joined by complete formation complex. During these steps, two critical events occur: selects for translation specific from among species mRNAs; interacts initiator site on assure proper in correct phase. reactions are promoted or catalyzed array factors involve hydrolysis ATP GTP.
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