Evaluation of serum procalcitonin concentration in the ICU following severe burn.

作者: L. Bargues , Y. Chancerelle , J. Catineau , P. Jault , H. Carsin

DOI: 10.1016/J.BURNS.2006.10.401

关键词: ProcalcitoninBacteremiaReceiver operating characteristicGastroenterologyMedicineSepsisTotal body surface areaSevere burnWhite blood cellInternal medicineMechanical ventilationSurgery

摘要: Abstract The goal of the study was to analyse plasma procalcitonin (PCT) concentrations during infectious events burns in ICU. Clinical and laboratory data were collected at admission twice a week burned patients admitted with total body surface area (TBSA) >20%. Procalcitonin determined using both semi-quantitative detection (PCT-Q®) quantitative immunoluminometric method (PCT-Lumi®). A 359 time points 25 consecutive 40 ± 17% (20–86%) TBSA burned, defined as concentration associated an inflammatory status according society critical care medicine definition, made. principal site infection respiratory tract (84% required mechanical ventilation). PCT-Lumi® values corresponded four ranges PCT-Q® statistically reflected simultaneously observed (Kruskall–Wallis test). under receiver operating characteristic curve for C-reactive protein (CRP) higher than those PCT white blood cell (WBC) count, but this difference not significant. optimum cut-off value 0.534 ng/ml sensitivity specificity 42.4% 88.8%, respectively. However, does appear be superior count diagnosis marker sepsis burns. is sufficient diagnose follow

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